Follow the A5025 after crossing the Menai Straits by the Britannia Bridge (A55) and take junction 8 for Amlwch/Benllech. Turn right and then follow the road until you have gone through Benllech and reached the roundabout at the Moelfre. Turn to the left and drive towards Amlwch until you come to the village of Brynrefail.
There is a small bus terminus on the left hand side of the road. Turn right here (there is a brown sign directing you to Tyddyn Môn) and continue down the narrow road (keeping to the right down the no through road) for about 100 yards. The entrance to Tyddyn Môn is clearly sign posted on the right.
SAT NAV Postcode: LL70 9PJ